The depletion attraction: an underappreciated force driving cellular organization

نویسندگان

  • Davide Marenduzzo
  • Kieran Finan
  • Peter R. Cook
چکیده

Cellular structures are shaped by hydrogen and ionic bonds, plus van der Waals and hydrophobic forces. In cells crowded with macromolecules, a little-known and distinct force-the "depletion attraction"-also acts. We review evidence that this force assists in the assembly of a wide range of cellular structures, ranging from the cytoskeleton to chromatin loops and whole chromosomes.

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عنوان ژورنال:
  • The Journal of Cell Biology

دوره 175  شماره 

صفحات  -

تاریخ انتشار 2006